Journal Articles

28.    Cabrera A.P., Bhaskaran A, Xu J, Yang X, Scott H.A., Mohideen U, Ghosh K. Senescence increases choroidal endothelial stiffness and susceptibility to complement injury: Implications for choriocapillaris loss in AMD. Investigative Ophthalmology & Visual Science (2016); 57(14):5910-5918. Pubmed Link


 27.    Mohan R.R., Cabrera A.P., Harrison R.E., Gorham R.D., Johnson L.V., Ghosh K, and Morikis D. Peptide redesign for inhibition of the complement system: Targeting age-related macular degeneration. Molecular Vision (2016); 22: 1280-1290. Pubmed Link

26.    Scott, H.A., Quach, B., Yang, X., Ardekani, S., Cabrera, A.P., Wilson, R., Messaoudi-Powers, I. and Ghosh, K. Matrix Stiffness Exerts Biphasic Control Over Monocyte-Endothelial Adhesion via Rho-mediated ICAM-1 Clustering. Integrative Biology (2016); 8(8):869-78 Pubmed Link

25.    Monickaraj, F., McGuire, P.G., Nitta, C.F., Ghosh, K. and Das, A. Cathepsin D: an Mϕ-derived factor mediating increased endothelial cell permeability with implications for alteration of the blood-retinal barrier in diabetic retinopathy. The FASEB Journal (2016); 30(4):1670-82. Pubmed Link

24.    Yang, X., Scott, H.A., Monickaraj, F., Xu, J., Ardekani, S., Nitta, C.F., Cabrera, A., McGuire, P.G., Mohideen, U., Das, A. and Ghosh, K. Basement membrane stiffening promotes retinal endothelial activation associated with diabetes. The FASEB Journal (2016); 30(2):601-6011. Pubmed Link

23.    Adapala, R.K., Thoppil, R.J., Ghosh, K., Cappelli, H.C., Dudley, A.C., Paruchuri, S., Keshamouni, V., Klagsbrun, M., Meszaros, J.G., Chilian, W.M. and Ingber, D.E. Activation of mechanosensitive ion channel TRPV4 normalizes tumor vasculature and improves cancer therapy. Oncogene (2016); 35(3):314-22. Pubmed Link

22.    Ardekani, S., Scott, H.A., Gupta, S., Eum, S., Yang, X., Brunelle, A.R., Wilson, S.M., Mohideen, U. and Ghosh, K. Nanoliposomal Nitroglycerin Exerts Potent Anti-Inflammatory Effects. Scientific Reports (2015); 5:16258 Pubmed Link

21.    Adini, I., and Ghosh, K. Mouse Retinal Whole Mounts and Quantification of Vasculature Protocol. Bio-Protocol (2015); 5(15):e1546  Article Link

20.    Yang X, Scott HA, Ardekani S, Williams M, Talbot P, Ghosh K. Aberrant Cell and Basement Membrane Architecture Contribute to Sidestream Smoke-Induced Choroidal Endothelial Dysfunction. Investigative Ophthalmology & Visual Science (2014); 55(5):3140-3147. Pubmed Link

19.    Adini, I., Ghosh, K., Adini, A., Chi, Z.L., Yoshimura, T., Benny, O., Connor, K.M., Rogers, M.S., Bazinet, L., Birsner, A.E. and Bielenberg, D.R. Melanocyte-secreted fibromodulin promotes an angiogenic microenvironment. The Journal of Clinical Investigation (2014); 124(1):425-436.  Pubmed Link

18.    Pan, Z., Ghosh, K., Hung, V., Macri, L.K., Einhorn, J., Bhatnagar, D., Simon, M., Clark, R.A. and Rafailovich, M.H. Deformation gradients imprint the direction and speed of en masse fibroblast migration for fast healing. Journal of Investigative Dermatology (2013); 133(10):2471-2479. Pubmed Link

17.    Adini, A., Adini, I., Ghosh, K., Benny, O., Pravda, E., Hu, R., Luyindula, D. and D’Amato, R.J. The stem cell marker prominin-1/CD133 interacts with vascular endothelial growth factor and potentiates its action. Angiogenesis (2013); 16(2):405-416. Pubmed Link 

16.   Korin, N., Kanapathipillai, M., Matthews, B.D., Crescente, M., Brill, A., Mammoto, T., Ghosh, K., Jurek, S., Bencherif, S.A., Bhatta, D. and Coskun, A.U. Shear-activated nanotherapeutics for drug targeting to obstructed blood vessels. Science (2012); 337(6095):738-742. Pubmed Link

15.    Kanapathipillai, M., Mammoto, A., Mammoto, T., Kang, J.H., Jiang, E., Ghosh, K., Korin, N., Gibbs, A., Mannix, R. and Ingber, D.E. Inhibition of mammary tumor growth using lysyl oxidase-targeting nanoparticles to modify extracellular matrix. Nano Letters (2012); 12(6):3213-3217. Pubmed Link

14.    Ghosh, K., Kanapathipillai, M., Korin, N., McCarthy, J.R. and Ingber, D.E. Polymeric nanomaterials for islet targeting and immunotherapeutic delivery. Nano letters (2011); 12(1):203-208. Pubmed Link

13.    Liu, Y., Ji, Y., Ghosh, K., Clark, R.A., Huang, L. and Rafailovich, M.H. "Effects of fiber orientation and diameter on the behavior of human dermal fibroblasts on electrospun PMMA scaffolds. Journal of Biomedical Materials Research Part A  (2009); 90(4):1092-1106. Pubmed Link

12.    Pan, Z., Ghosh, K., Liu, Y., Clark, R.A. and Rafailovich, M.H. Traction stresses and translational distortion of the nucleus during fibroblast migration on a physiologically relevant ECM mimic. Biophysical Journal(2009); 96(10):4286-4298. Pubmed Link

11.    Thodeti, C.K., Matthews, B., Ravi, A., Mammoto, A., Ghosh, K., Bracha, A.L. and Ingber, D.E. TRPV4 channels mediate cyclic strain–induced endothelial cell reorientation through integrin-to-integrin signaling. Circulation Research (2009); 104(9):1123-1130. Pubmed Link

10.    Ghosh, K., Thodeti, C.K., Dudley, A.C., Mammoto, A., Klagsbrun, M. and Ingber, D.E. Tumor-derived endothelial cells exhibit aberrant Rho-mediated mechanosensing and abnormal angiogenesis in vitro. Proceedings of the National Academy of Sciences (2008); 105(32):11305-11310. Pubmed Link

9.      Ghosh, K. and Ingber, D.E. Micromechanical control of cell and tissue development: implications for tissue engineering. Advanced Drug Delivery Reviews (2007); 59(13):1306-1318. Pubmed Link

8.      Clark, R.A., Ghosh, K. and Tonnesen, M.G. Tissue engineering for cutaneous wounds. Journal of Investigative Dermatology (2007); 127(5):1018-1029. Pubmed Link

7.      Ghosh, K., Pan, Z., Guan, E., Ge, S., Liu, Y., Nakamura, T., Ren, X.D., Rafailovich, M. and Clark, R.A. Cell adaptation to a physiologically relevant ECM mimic with different viscoelastic properties. Biomaterials (2007); 28(4):671-679. Pubmed Link

6.      Ji, Y., Ghosh, K., Li, B., Sokolov, J.C., Clark, R.A. and Rafailovich, M.H. Dual‐Syringe Reactive Electrospinning of Cross‐Linked Hyaluronic Acid Hydrogel Nanofibers for Tissue Engineering Applications. Macromolecular Bioscience (2006);  6(10):811-817. Pubmed Link

5.      Mehra, T.D., Ghosh, K., Shu, X.Z., Prestwich, G.D. and Clark, R.A. Molecular stenting with a crosslinked hyaluronan derivative inhibits collagen gel contraction. Journal of Investigative Dermatology (2006); 126(10):2202-2209. Pubmed Link

4.      Ji, Y., Ghosh, K., Shu, X.Z., Li, B., Sokolov, J.C., Prestwich, G.D., Clark, R.A. and Rafailovich, M.H. Electrospun three-dimensional hyaluronic acid nanofibrous scaffolds. Biomaterials (2006); 27(20):3782-3792. Pubmed Link

3.      Ghosh, K., Ren, X.D., Shu, X.Z., Prestwich, G.D. and Clark, R.A. Fibronectin functional domains coupled to hyaluronan stimulate adult human dermal fibroblast responses critical for wound healing. Tissue Engineering(2006); 12(3):601-613. Pubmed Link

2.      Ghosh, K., Shu, X.Z., Mou, R., Lombardi, J., Prestwich, G.D., Rafailovich, M.H. and Clark, R.A. Rheological characterization of in situ cross-linkable hyaluronan hydrogels. Biomacromolecules (2005); 6(5):2857-2865. Pubmed Link

1.      Shu, X.Z., Ghosh, K., Liu, Y., Palumbo, F.S., Luo, Y., Clark, R.A. and Prestwich, G.D. Attachment and spreading of fibroblasts on an RGD peptide–modified injectable hyaluronan hydrogel. Journal of Biomedical Materials Research Part A (2004); 68(2):365-375. Pubmed Link